The cell-free DNA prenatal screening involves a non-invasive, diagnostic test that detects certain conditions caused by an abnormal number of chromosomes. For more info on cell-free DNA testing in Pune, get in touch with Dr Tejas Tamhane, a trusted fetal medicine specialist.
There is a quiet magic in the early months of pregnancy filled with tiny changes, everyday milestones and a world of hope growing day by day. Alongside all the excitement, it’s completely natural for expectant parents to look for information and reassurance. After all, every family wants to feel confident and supported as they await the arrival of their little one.
In recent years, one test that has stood out in helping understand a baby’s wellbeing early in pregnancy is the cell-free DNA test, also known as NIPT. At Precious Clinic for Advanced Fetal Medicine, we often meet parents who have heard the term but are not sure what it truly means, how it works or why it is recommended.
What Is Cell-free DNA Test & Why Does It Matter?
During pregnancy, tiny fragments of the baby’s DNA circulate in the mother’s bloodstream. These fragments are known as cell-free DNA (cfDNA) and they come mostly from the placenta, which closely reflects the baby’s genetic material.
NIPT analyses this DNA from a simple maternal blood sample to detect the likelihood of common chromosomal conditions in the baby, such as:
- Down syndrome (Trisomy 21)
- Edwards syndrome (Trisomy 18)
- Patau syndrome (Trisomy 13)
- Sex chromosome variations
It’s important to note that NIPT is a screening test, not a diagnostic one. It tells us the probability of a condition, not a confirmed diagnosis. If the result comes back high-risk, further testing such as CVS or amniocentesis is done to be certain.
Why Cell-free DNA Test?
What makes the cell-free DNA test or NIPT so special than the other is its simplicity and safety. It does not disturb the pregnancy in any way. No needles near the baby, no invasive procedures and no discomfort for the mother beyond a routine blood draw.
When Is It Done?
A cell-free DNA test can be done as early as 10 weeks of pregnancy.
The Science Behind NIPT
In simple terms, the test looks for genetic patterns that may benefit from closer attention and give doctors the info they need without disturbing the pregnancy.
Once the blood sample is collected, advanced technology is used to separate the fetal DNA fragments from the mother’s DNA. The fetal DNA is then studied and if there are more copies of a particular chromosome than expected, it signals a higher chance of that chromosomal condition.
(Also Read: Sickle Cell Testing During Pregnancy In Pune – Dr Tejas Tamhane)
Results
Most test results arrive within one to two weeks. When it comes back as low-risk, it brings a sense of relief and calm. When it raises concerns, our priority is to sit with parents, explain things and answer every question that we can.
Cell-free DNA Testing In Pune – Consult Dr Tejas Tamhane
NIPT is an integral part of prenatal care that allows us to assess chromosomal risks with higher accuracy and lower procedural risk. While it does not replace diagnostic procedures, it serves as an important first-line tool in identifying pregnancies that require further evaluation.
Are you or a loved one looking to get a cell-free DNA test in Pune? Then, consult Dr Tejas Tamhane, the best fetal medicine specialist in Pune, for the right guidance.
